Leucism is a condition in which there is partial loss of pigmentation in an animal - which causes white, pale, or patchy coloration of the skin, hair, feathers, scales or cuticle, but not the eyes. It is occasionally spelt leukism. Unlike albinism, it can cause a reduction in multiple types of pigment, not just melanin.

Leucism is a general term for the phenotype that results from defects in pigment cell differentiation and/or migration from the neural crest to skin, hair, or feathers during development. This results in either the entire surface (if all pigment cells fail to develop) or patches of body surface (if only a subset are defective) having a lack of cells that can make pigment.

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