Apitoxin, or honey bee venom, is a bitter colourless liquid. Its active portion a mixture of proteins, which causes local inflammation and acts as an anticoagulant. A honeybee can inject 0.1 mg of venom via its stinger.

A honey bee (or honeybee) is any bee member of the genus Apis, primarily distinguished by the production and storage of honey and the construction of perennial, colonial nests from wax. The best known honey bee is the Western honey bee which has been domesticated for honey production and crop pollination. Honey bees represent only a small fraction of the roughly 20,000 known species of bees. Some other types of related bees produce and store honey, including the stingless honey bees, but only members of the genus Apis are true honey bees. The study of bees including honey bees is known as melittology.

Bee venom therapy, or apitherapy, uses the stings of live bees to relieve symptoms of MS such as pain, loss of coordination, and muscle weakness. Apitherapy researchers suggest that certain compounds in bee venom, namely melittin and adolapin, help reduce inflammation and pain.

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