"Moon River" is a song composed by Henry Mancini with lyrics by Johnny Mercer. It received an Academy Award for Best Original Song for its performance by Audrey Hepburn in the movie Breakfast at Tiffany's (1961). It also won Mancini the 1962 Grammy Award for Record of the Year and won Mancini and Mercer the Grammy Award for Song of the Year. The song has been covered by many other artists.

Mercer and Mancini wrote the song for Audrey Hepburn to fit her vocal range. The lyrics, written by Mercer, are reminiscent of his childhood in Savannah, Georgia, including its waterways. As a child, he had picked huckleberries in summer, and connected them with a carefree childhood and Mark Twain's Huckleberry Finn. Although an instrumental version is played over the film's opening titles, the lyrics are first heard in a scene where Paul "Fred" Varjak (George Peppard) discovers Holly Golightly (Hepburn) singing them, accompanied by her guitar, on the fire escape outside their apartments.

Breakfast at Tiffany's is a 1961 American romantic comedy film directed by Blake Edwards and written by George Axelrod, loosely based on Truman Capote's novella of the same name. Starring Audrey Hepburn and George Peppard, and featuring Patricia Neal, Buddy Ebsen, Martin Balsam, and Mickey Rooney, the film was initially released on October 5, 1961 by Paramount Pictures.

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