Emma Rose Roberts was born in Rhinebeck, New York, to Kelly Cunningham and actor Eric Roberts. Her parents separated when she was a baby. Through her father's marriage, she is the stepdaughter of Eliza Roberts. Through her mother's marriage, she is the stepdaughter of musician Kelly Nickels. She has a maternal half-sister, Grace. Her paternal grandmother was acting coach Betty Lou Bredemus (1934–2015), and her aunts are actresses Julia Roberts and Lisa Roberts Gillan. During her childhood, Roberts spent time on the sets of her aunt Julia's films. These experiences sparked a desire to follow her father and aunts into the film industry. Her mother initially wanted her to have a normal childhood.

After small roles in films such as Blow (2001), she rose to prominence with her role as Addie Singer in the Nickelodeon television series Unfabulous (2004–07), for which she was nominated for a Teen Choice Award and six Young Artist Awards. She released her debut album, which also served as the show's soundtrack, Unfabulous and More in 2005.

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