Enterprise is the cross-border inter-city train service between Dublin Connolly in the Republic of Ireland and Belfast Central in Northern Ireland, jointly operated by Iarnród Éireann (IE) and NI Railways (NIR). It operates on the Belfast–Dublin railway line.

The Great Northern Railway (Ireland) (GNR(I)) introduced the service as the "Enterprise Express" on 11 August 1947 in an attempt to compete with air and road transport which were challenging the railways. In particular, business travel was and is an important market. Customs checks were limited to the Belfast and Dublin terminals to reduce journey times by ensuring that journeys were non-stop, and advance booking was available. Apparently the name of the train comes from "the enterprising approach" that the GNR(I) took to make journeys more convenient for passengers despite the requirement for customs checks. The initial service ran between Belfast Great Victoria Street station and Dublin Amiens Street station, which was renamed Dublin Connolly in 1966. Locomotives of GNRI Class V were initially used, followed in 1948 by GNRI Class VS.

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