'The No. 1 Ladies' Detective Agency' is a series of novels by Alexander McCall Smith set in Botswana and featuring the character Mma Precious Ramotswe. The series is named for the first novel, published in 1998. Eighteen novels have been published in the series between 1998 and 2017.

Mma Precious Ramotswe is the main character in this series. The country of Botswana is in a sense a character as well, as it is a crucial aspect of how the stories flow. Mma Ramotswe starts up her detective agency when she is 34 years old, using the inheritance from her father to move to the capital city Gaborone to buy a house for herself and find an office for her new business. She feels a detective needs to know about people more than anything, to solve problems for them. The novels are as much about the adventures and foibles of different characters as they are about solving mysteries. Each book in the series follows from the previous book.

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