One Shell Square is a 51-story, 697-foot (212 m) skyscraper located at 701 Poydras Street in the Central Business District of New Orleans, Louisiana. It is the tallest building in both the city of New Orleans and the state of Louisiana, and is taller than Louisiana's tallest peak, Driskill Mountain. The building is primarily used for leaseable office space, with some retail space on the ground level. Shell Oil Company is the building's largest tenant. Current occupancy of the building is approximately 90 percent.

The exterior of the building is clad in Italian limestone and bronze glass. There has been concern over the years regarding the limestone's integrity during severe weather such as tropical systems. Fortunately, these fears did not play out during Hurricane Katrina in August 2005 and the building weathered the storm with minimal damage, such as blown out windows and rain damage. The building reopened to tenants in December 2005.

At the time of its completion in 1972, One Shell Square was the tallest building in the Southeast, surpassing the Wachovia Bank of Georgia Building in Atlanta. It held the title of the Southeast's tallest building until 1976, when the Westin Peachtree Plaza in Atlanta surpassed it. It has an emergency heliport and its own zip code.

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