St. Enoch station was a mainline railway station in the city of Glasgow, Scotland between 1876 and 1966. It was demolished in 1977. The hotel was the first building in Glasgow to be fitted out with electric lighting.

It was a large station with 12 platforms and two impressive semi-cylindrical glass/iron roofed train sheds. The station was closed on 27 June 1966 as part of the rationalisation of the railway system undertaken by the British Railways Board chairman Dr. Richard Beeching; upon closure its 250 trains and 23,000 passengers a day were diverted to Central. The roofs of the structure were demolished, despite protests, in 1977. The clock that was suspended from the roof of the station was saved from destruction and is now on display in Cumbernauld Town Centre.

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