Harpagophytum procumbens, also called grapple plant, wood spider and most commonly devil's claw, is a genus of plants in the sesame family, native to southern Africa. Plants of the genus owe their common name "devil's claw" to the peculiar appearance of their hooked fruit. Several species of North American plants in genus Proboscidea and certain species of Pisonia are however also known by this name. Devil's claw's tuberous roots are used in folk medicine to reduce pain.

H. procumbens is mainly found in the eastern and south eastern parts of Namibia, Southern Botswana and the Kalahari region of the Northern Cape, South Africa.

The ethnobotanical use of devil's claw originated in southern Africa. H. procumbens is one of the floral emblems of Botswana where it is thought to be useful in treating a variety of pain conditions.

The name, devil's claw, is derived from the thorny barbs on its unusual fruit. It appears to be covered with numerous small hooks. Herbalists believe it stimulates the stomach to increase production of acid, which improves digestion. Its storage roots contain the active ingredients.

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