Kinsey Millhone is a fictional character who was created by Sue Grafton for her "alphabet mysteries" series of novels. Millhone appears in a number of short stories written by Grafton. Grafton's mystery novels featuring Millhone are set in 1980s Santa Teresa, a fictionalized town based on Santa Barbara, California.

The fictional character Kinsey Millhone was born on May 5, 1950. Her unusual first name was the maiden name of her mother, wealthy debutante Rita Cynthia Kinsey, who married Kinsey's father, Randy Millhone, against the wishes of Kinsey's grandmother, Cornelia LaGrand Kinsey (Grand), causing a family rift. Kinsey's parents were killed in a car wreck when she was five; Kinsey was trapped in the car with her dead parents for several hours before she was rescued. She then moved in with her mother's sister Virginia (Aunt Gin), the only relative to side with Rita in the family rift, although Kinsey later finds out her parents were en route to a bridge-building family visit when the accident occurred.

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