The men's singles tennis tournament at the 2012 Olympic Games in London was held at the All England Club in Wimbledon from 28 July to 5 August, making it the first Olympic grass court tournament since tennis was re-introduced to the Games. The event was run and organised by the International Olympic Committee (IOC) and the International Tennis Federation (ITF), and is part of the Association of Tennis Professionals tour. Matches were the best of three sets, except for the final which was the best of five sets. Tie-breaks were in use for all sets except the fifth set of the final and the third set of all other matches.

Great Britain's Andy Murray defeated Federer in the final, 6–2, 6–1, 6–4, to win the gold medal. Del Potro, representing Argentina, took bronze courtesy of a 7–5, 6–4, victory over 2008 bronze medalist Djokovic.

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