The skeleton of most snakes consists solely of the skull, hyoid, vertebral column, and ribs, though henophidian snakes retain vestiges of the pelvis and rear limbs.

The vertebral column consists of anywhere between 200 and 400 (or more) vertebrae. Tail vertebrae are comparatively few in number (often less than 20% of the total) and lack ribs, while body vertebrae each have two ribs articulating with them. The vertebrae have projections that allow for strong muscle attachment enabling locomotion without limbs.

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