The line: "Game over, man. Game over!" is from which motion picture?

The line: "Game over, man. Game over!" is from the 1986 U.S. science fiction action film "Aliens". 'Game over' is used as a phrase to concede final and total defeat. In the movie "Aliens", one of the protagonists, Private William Hudson (Bill Paxton), shouts, "Game over, man. Game over!" The words are specifically spoken once the ship meant to rescue Hudson and his expedition is utterly destroyed.

In this acclaimed sequel, the only survivor from the first film, Lt. Ripley (Sigourney Weaver), finds her horrific account of her crew's fate is met with skepticism. Things change once the disappearance of colonists on LV-426 prompts a team of high-tech U.S. Marines to investigate. Ripley travels with the team as an advisor, only to find that her biggest fear has come true.

"Aliens" was directed by James Cameron and produced by Gale Anne Hurd. The screenplay was written by Cameron. The film's story was fully developed by Cameron, David Giler, and Walter Hill. The key cast members were: Sigourney Weaver, Michael Biehn, Paul Reiser, Lance Henriksen, Carrie Henn, Bill Paxton, William Hope, Jenette Goldstein, Mark Rolston, and Al Matthews. This fantasy horror film had its public released in July 1986 and grossed $180 million worldwide.

"Aliens" was nominated for 7 Academy Awards, including a Best Actress nomination for Sigourney Weaver. It won Oscars for both Sound Effects Editing and Visual Effects.