Valletta is the capital city of Malta. Located in the South Eastern Region of the main island, between Marsamxett Harbour to the west and the Grand Harbour to the east. The harbour, historically also referred to as Marsamuscetto, is a natural harbour on the island of Malta. The harbour is generally more dedicated to leisure use than the Grand Harbour.

The harbour mouth faces north east and is bounded to the north by Dragut Point and Tigné Point. Its northwest shore is made up of the towns of Sliema, Gżira and Ta' Xbiex. The harbour then extends inland to Pietà and Msida. Off Gżira lies Manoel Island, now connected to the mainland by a bridge.

The south eastern shore of the harbour is formed by the Sciberras peninsula, which is largely covered by the town of Floriana and the city of Valletta. At its tip lies the 16th century Fort Saint Elmo. The Sciberras peninsula divides Marsamxett from the larger parallel natural harbour, Grand Harbour.

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