"Jingle Bells" was the first song broadcast from space.

Nine days before Christmas in 1965, the two astronauts aboard Gemini 6 had just completed a rendezvous with Gemini 7 when the crew suddenly gave a troubling report to Mission Control: “We have an object, looks like a satellite going from north to south, up in a polar orbit. He’s in a very low trajectory traveling from north to south and has a very high climbing ratio. It looks like it might even be a … Very low. Looks like he might be going to reenter soon. Stand by one … You might just let me try to pick up that thing.” The tense report of the unidentified flying object was suddenly broken by the sound of “Jingle Bells” with “Wally” Schirra playing a tiny harmonica accompanied by Tom Stafford shaking a handful of small sleigh bells they had brought along for the space voyage.

More Info: en.wikipedia.org