The Zarate-Brazo Largo Bridges are two cable-stayed road and railway bridges in Argentina, crossing the Paraná River (Paraná Guazú and Paraná de las Palmas) between the cities of Zarate, Buenos Aires Province, and Brazo Largo, Entre Ríos Province.

The bridges have a suspended length of 550 m (1,804 ft), with a main span of 330 m (1,083 ft). Its pylons are 110 m (361 ft) high, and its deck depth is 2.6 m (8.5 ft). The road link has four lanes. The main span is 50 m (164 ft) over the water level of the Paraná, which allows the passage of very large ships. It is one of only two such bridges over the Paraná, the other being the more recent Rosario-Victoria Bridge (2003).

The 20-mile- (33-km-) long system of bridges, roadways, and railways was completed in the late 1970s extending north from Zárate across the Paraná delta; for the first time, direct transportation links between the Argentine Mesopotamia and Buenos Aires regions were established.

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