Which of these is one of the world's most well-known areas of wine production?

The Loire Valley wine region is one of the world's most well-known areas of wine production and includes several French wine regions situated along the river from the Muscadet region on the Atlantic coast to the regions of Sancerre and Pouilly-Fumé just southeast of the city of Orléans in north-central France. Loire wines tend to exhibit a characteristic fruitiness with fresh, crisp flavors.

The area of the Loire Valley comprises about 800 square kilometres (310 sq mi). It is referred to as the Cradle of the French and the Garden of France due to the abundance of vineyards, fruit orchards (such as cherries), and artichoke, and asparagus fields, which line the banks of the river. Notable for its historic towns, architecture, and wines, the valley has been inhabited since the Middle Palaeolithic period. In 2000, UNESCO added the central part of the Loire River valley to its list of World Heritage Sites.