The muskellunge (Esox masquinongy), also known as muskelunge, muscallonge, milliganong, or maskinonge (and often abbreviated "muskie" or "musky"), is a species of large, relatively uncommon freshwater fish native to North America. The muskellunge is the largest member of the pike family, Esocidae. The common name comes from the Ojibwa word maashkinoozhe, meaning "ugly pike", by way of French masque allongé (modified from the Ojibwa word by folk etymology), "elongated face." The French common name is masquinongé or maskinongé.

The muskellunge is known by a wide variety of trivial names including Ohio muskellunge, Great Lakes muskellunge, barred muskellunge, Ohio River pike, Allegheny River pike, jack pike, unspotted muskellunge and the Wisconsin muskellunge.

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