Crabbe's role in the 1933 Tarzan serial, Tarzan the Fearless, began a career in which he starred in more than one hundred movies. In the 1933 King of the Jungle, 1941 Jungle Man, and the 1952 serial King of the Congo, he played typical "jungle man" roles. He starred in several popular films at this time, including The Sweetheart of Sigma Chi alongside Betty Grable in 1933 and Search for Beauty (1934), and in 1936 he was Flash Gordon in the very successful Flash Gordon serial, followed by two sequels, released by Universal in 1938 and 1940.

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