Douglas-Home, then known as Lord Dunglass, was a talented sportsman. In addition to representing Eton at Fives, he was a capable cricketer at school, club and county level, and was unique among British prime ministers in having played first-class cricket. Wisden observed, "In the rain-affected Eton-Harrow match of 1922 he scored 66, despite being hindered by a saturated outfield, and then took 4 for 37 with his medium-paced out-swingers".

At first-class level he represented the Oxford University Cricket Club, Middlesex CCC and MCC. Between 1924 and 1927 he played ten first-class matches, scoring 147 runs at an average of 16.33 with a best score of 37 not out. As a bowler he took 12 wickets at an average of 30.25 with a best of 3 for 43. Three of his first-class games were internationals against Argentina on the MCC "representative" tour of South America in 1926–27.

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