U.S. Route 66 (US 66 or Route 66), also known as the Will Rogers Highway, the Main Street of America or the Mother Road, was one of the original highways within the U.S. Highway System. US 66 was established on November 11, 1926, with road signs erected the following year. The highway, which became one of the most famous roads in the United States, originally ran from Chicago, Illinois through Missouri, Kansas, Oklahoma, Texas, New Mexico and Arizona before ending at Santa Monica, California. It covered a total of 2,448 miles. It was recognized in popular culture by both the hit song "(Get Your Kicks on) Route 66" and the "Route 66" television show in the 1960s.

US 66 underwent many improvements and realignments over its lifetime, and it was officially removed from the United States Highway System in 1985, after it had been replaced in its entirety by segments of the Interstate Highway System.

Over the years, thousands motored along this relic of cherished Americana. Historic hotels, neon–wrapped diners and natural wonders attracted road trippers. Both regular folks and celebrities were drawn to its sites. Elvis often stayed at the Best Western Trade Winds Motel in Clinton, Oklahoma. Clark Gable frequented Arizona's Oatman Hotel. John Steinbeck's 1937 drive west along the route inspired him to write "The Grapes of Wrath". Nowadays, most drivers take interstate highways but, if you want to slow down and "get your kicks", Route 66 waits for you.

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