Of course the larger, more populous cities I-20 runs through are Atlanta and Augusta GA; Meridian, Jackson & Vicksburg MS; Dallas-Fort Worth TX; Columbia, Aiken & North Augusta SC; & Monroe (represented in accompanying uploaded photo), West Monroe & Shreveport-Bossier City LA.

The eastern end of I-20 is Florence SC spawning off I-95 while it terminates westward into I-10 near the small towns Kent & Scroggins Draw TX after passing through the Permian River Basin cities Midland & Odessa.

More Info: en.m.wikipedia.org