Of the 56 signers of the U.S. Declaration of Independence, only two would become president of the United States. The two future presidents were John Adams and Thomas Jefferson. In light of what George Washington accomplished during his life, it is often believed that he was a signer of the U.S. Declaration of Independence and later became the first person to be a U.S. President. This belief is totally false. George Washington was not available and didn't sign the document in 1776.

John Adams (1735 – 1826) from the state of Massachusetts was the second President of the United States from March 1797 – March 1801. His Vice President was Thomas Jefferson. He was preceded by George Washington and succeeded by Thomas Jefferson. During his life, Adams was a lawyer, diplomat, and political theorist. He was seen as a dedicated diarist and correspondent, particularly with his cherished wife Abigail. Adams' signature appears on the right side of the Declaration of Independence.

Thomas Jefferson (1743 – 1826) from the state of Virginia became the third President of the United States. He served as president from March 1801 – March 1809. His Vice Presidents were Aaron Burr (1801–1805) and George Clinton (1805–1809). Jefferson was preceded by John Adams and succeeded by James Madison. Jefferson was a strong proponent of democracy, republicanism, and individual rights. Jefferson's signature is located 5th from the bottom and in the center of Declaration of Independence.

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