Grape juice is obtained from crushing and blending grapes into a liquid. In the wine industry, grape juice that contains 7–23 percent of pulp, skins, stems and seeds is often referred to as must. The sugars in grape juice allow it to be used as a sweetener, and fermented and made into wine, brandy, or vinegar. In North America, the most common grape juice is purple and made from Concord grapes while white grape juice is commonly made from Niagara grapes, both of which are varieties of native American grapes.

The method of pasteurizing grape juice to halt fermentation has been attributed to an American physician and dentist, Thomas Bramwell Welch, in 1869. A supporter of the temperance movement, he produced a non-alcoholic wine to be used for church services in his hometown of Vineland, New Jersey. His fellow parishioners continued to prefer and use regular wine. His son, Charles E. Welch, who was also a dentist, eventually gave up his practice to promote grape juice. In 1893, he founded Welch's Grape Juice Company at Westfield, New York.

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