In the biblical Book of Genesis, Cain and Abel are the first two sons of Adam and Eve. Cain, the firstborn, was a farmer, and his brother Abel was a shepherd.

According to the Book of Genesis, Cain is the first child of Eve, the first murderer, and the third human being to fall under a curse. According to Genesis 4:1–16, Cain treacherously murdered his brother Abel, lied about the murder to God, and as a result was cursed and marked for life. With the earth left cursed to drink Abel's blood, Cain was no longer able to farm the land. Cain is punished as a "fugitive and wanderer". He receives a mark from God, commonly referred to as the mark of Cain, representing God's promise to protect Cain from being murdered.

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