How many denominations of currency has the United States printed for general circulation that have been larger than $20?

Since the founding of the United States, the US Treasure Department has printed 6 denominations of paper currency for general circulation that have been larger in value than the $20 bill. There was 1 additional bill printed valued at $100,000 that was not for general circulation. This was used for exchanges between banks and for other governmental purposes but not for the general public usage.

The denominations that have been printed that are larger than the $20 bill are; $50, $100, $500, $1,000, $5,000 and the $10,000. The four larger denominations were discontinued by executive order of President Nixon.

The Federal Reserve began taking high-denomination currency out of circulation (destroying large bills received by banks) in 1969, after an executive order by President Nixon. As of May 30, 2009, only 336 - $10,000 bills were known to exist; 342 remaining $5,000 bills; and 165,372 remaining $1,000 bills. Due to their rarity, collectors often pay considerably more than the face value of the bills to acquire them. Some are in museums in other parts of the world.