Lake Vostok is the largest of Antarctica's almost 400 known subglacial lakes. Lake Vostok is located at the southern Pole of Cold, beneath Russia's Vostok Station under the surface of the central East Antarctic Ice Sheet, which is at 3,488 m (11,444 ft) above mean sea level. The surface of this fresh water lake is approximately 4,000 m (13,100 ft) under the surface of the ice, which places it at approximately 500 m (1,600 ft) below sea level.

Measuring 250 km (160 mi) long by 50 km (30 mi) wide at its widest point, it covers an area of 12,500 km2 (4,830 sq mi) making it the 16th largest lake by surface area. With an average depth of 432 m (1,417 ft), it has an estimated volume of 5,400 km3 (1,300 cu mi), making it the 6th largest lake by volume.

The lake is divided into two deep basins by a ridge. The liquid water depth over the ridge is about 200 m (700 ft), compared to roughly 400 m (1,300 ft) deep in the northern basin and 800 m (2,600 ft) deep in the southern.

The lake is named after Vostok Station, which in turn is named after the Vostok, a sloop-of-war, which means "East" in Russian. The existence of a subglacial lake in the Vostok region was first suggested by Russian geographer Andrey Kapitsa based on seismic soundings made during the Soviet Antarctic Expeditions in 1959 and 1964 to measure the thickness of the ice sheet.

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