The "Speedy" character was introduced in 1951. The character was originally conceived by creative director George Pal of the Wade Ad Agency and designed by illustrator Wally Wood. Originally named Sparky, his name was changed to Speedy by sales manager Perry L. Shupert to align with that year's promotional theme, "Speedy Relief." Speedy appeared in over 200 TV commercials between 1954 and 1964. His body was one Alka-Seltzer tablet, while he wore another as a hat. In his original spots, he sang "Relief is just a swallow away"; in his 1978 revival he proclaimed Alka-Seltzer's virtues and sang the "Plop, plop, fizz, fizz, oh what a relief it is" song in his high, squeaky voice (provided by veteran juvenile voice actor Dick Beals ). In the early 1960's, a commercial showing two tablets dropping into a glass of water instead of the usual one caused sales to double. In December 2010, Alka-Seltzer began a series of new commercials featuring Speedy, using CGI effects to recreate the stop-motion puppetry of the 1950s and 1960s, with Speedy.

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