The use of the fist as a salute by communists and antifascists is first evidenced in 1924, when it was adopted for the Communist Party of Germany's Roter Frontkämpferbund ("Alliance of Red Front-Fighters"). In reaction, the Nazi Party adopted the well-known Roman salute two years later.

The gesture of the raised fist was apparently known in the United States as well, and is seen in a photograph from a May Day march in New York City in 1936. It is perhaps best known in this era from its use during the Spanish Civil War of 1936–1939, as a greeting by the Republican faction, and known as the "Popular Front salute" or the "anti-fascist salute".

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