Trans World Airlines Flight 800 (TWA 800) was a Boeing 747-100 that exploded and crashed into the Atlantic Ocean near East Moriches, New York, on July 17, 1996, at about 8:31 p.m. EDT, 12 minutes after takeoff from John F. Kennedy International Airport on a scheduled international passenger flight to Rome, with a stopover in Paris. All 230 people on board died in the crash; it is the third-deadliest aviation accident in U.S. history. Accident investigators from the National Transportation Safety Board (NTSB) traveled to the scene, arriving the following morning amid speculation that a terrorist attack was the cause of the crash.

The four-year NTSB investigation concluded with the approval of the Aircraft Accident Report on August 23, 2000, ending the most extensive, complex, and costly air disaster investigation in U.S. history to that time. The report's conclusion was that the probable cause of the accident was explosion of flammable fuel vapors in the center fuel tank. Although it could not be determined with certainty, the likely ignition source was a short circuit. Problems with the aircraft's wiring were found, including evidence of arcing in the Fuel Quantity Indication System (FQIS) wiring that enters the tank. The FQIS on Flight 800 is known to have been malfunctioning; the captain remarked on what he called "crazy" readings from the system approximately two minutes and thirty seconds before the aircraft exploded.

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