Chyme or chymus is the semi-fluid mass of partly digested food that is expelled by a person's stomach, through the pyloric valve, into the duodenum.

Chyme results from the mechanical and chemical breakdown of a bolus and consists of partially digested food, water, hydrochloric acid, and various digestive enzymes. Chyme slowly passes through the pyloric sphincter and into the duodenum, where the extraction of nutrients begins. Depending on the quantity and contents of the meal, the stomach will digest the food into chyme in some time from 40 minutes to 3 hours.

Chyle is a milky fluid that drains out from the small intestine during the digestion into the lymphatic system.

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