Regeneration is the natural process of replacing or restoring damaged or missing cells, tissues, organs, and even entire body parts to full function in plants and animals.

Some animals have extensive regenerative abilities. For example, the tiny freshwater animal called Hydra can form two whole bodies after being cut in half. The axolotl, or Mexican salamander, is an animal with a backbone that can regenerate the form and function of almost any limb, organ, or other body part.

Organisms regenerate in different ways. Plants and some sea creatures, such as jellyfish, can replace missing parts by extensively remodeling their remaining tissues.

Some animals such as lobsters, catfish, and lizards replace missing parts by first growing a blastema. The blastema cells rapidly divide to form the skin, scales, muscle, bone, or cartilage needed for creating the lost limb, fin, or tail.

In other animals, including humans, organs such as the liver undergo what’s called compensatory hypertrophy. When part of the liver is removed or destroyed, the remaining portion grows to the original size and allows the liver to function as it did before. Our kidneys, pancreas, thyroid, adrenal glands, and lungs compensate for organ loss in a similar, but more limited, way.

More Info: www.nigms.nih.gov