Which of these empires was the largest empire in pre-Columbian America?

The Inca Empire, also known as the Incan Empire and the Inka Empire, was the largest empire in pre-Columbian America. Its political and administrative structure is considered by most scholars to have been the most developed in the Americas before Columbus' arrival. The administrative, political and military center of the empire was located in the city of Cusco. The Inca civilization arose from the Peruvian highlands sometime in the early 13th century. Its last stronghold was conquered by the Spanish in 1572.

Notable features of the Inca Empire include its monumental architecture, especially stonework, extensive road network reaching all corners of the empire, finely-woven textiles, use of knotted strings for record-keeping and communication, agricultural innovations in a difficult environment, and the organization and management fostered or imposed on its people and their labor.