Which scientist greatly influenced reflex theory?

René Descartes ( 31 March 1596 – 11 February 1650) was a French philosopher, mathematician, and scientist. A native of the Kingdom of France, he spent about 20 years (1629–1649) of his life in the Dutch Republic after serving for a while in the Dutch States Army of Maurice of Nassau, Prince of Orange and the Stadtholder of the United Provinces. One of the most notable intellectual figures of the Dutch Golden Age, Descartes is also widely regarded as one of the founders of modern philosophy.

Descartes advanced a theory on automatic bodily reactions to external events which influenced 19th-century reflex theory. He argued that external motions such as touch and sound reach the endings of the nerves and affect the animal spirits. Heat from fire affects a spot on the skin and sets in motion a chain of reactions, with the animal spirits reaching the brain through the central nervous system, and in turn animal spirits are sent back to the muscles to move the hand away from the fire. Through this chain of reactions the automatic reactions of the body do not require a thought process.