U.S. Route 50 (US 50) is a transcontinental highway in the United States, stretching from West Sacramento, California, in the west to Ocean City, Maryland, on the east coast. The entire highway spans 3,017 mi (4855.39085 kms).

The Nevada portion crosses the center of the state and was named 'The Loneliest Road in America' by Life magazine in July, 1986. The name originates from large desolate areas traversed by the route, with few or no signs of civilization. US 50 has a diverse route through the state, traversing the resort communities of Lake Tahoe, the state capital in Carson City, historical sites such as Fort Churchill State Historic Park, petroglyphs, alpine forests, desert valleys, ghost towns, and Great Basin National Park.

'Loneliest Road' signs are scattered along the roadside, and some stores in the sparse towns along Route 50 display "I survived Route 50" signs in windows covered with geologic layers of grime.

More Info: en.wikipedia.org