Galena, also called lead glance, is the natural mineral form of lead(II) sulfide. It is the most important ore of lead and an important source of silver. Galena is one of the most abundant and widely distributed sulfide minerals. It crystallizes in the cubic crystal system often showing octahedral forms. It is often associated with the minerals sphalerite, calcite and fluorite.

Galena is the main ore of lead, used since ancient times. Because of its somewhat low melting point, it was easy to liberate by smelting.

In some deposits galena contains about 1–2% silver, a byproduct that far outweighs the main lead ore in revenue. Galena deposits often also contain significant amounts of silver as included silver sulfide mineral phases or as limited solid solution within the galena structure. These argentiferous galenas have long been the most important ore of silver.

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