The languages of Bolivia include Spanish; several dozen indigenous languages, most prominently Aymara, Quechua, Chiquitano, and Guaraní; Bolivian Sign Language (closely related to American Sign Language); and languages of immigrants such as Plautdietsch. The constitution says that all indigenous languages are official, listing 36 specific languages, of which some are extinct. Spanish and Quechua are spoken primarily in the Andes region, Aymara is mainly spoken in the Altiplano around Lake Titicaca, Chiquitano is spoken in the central part of Santa Cruz, and Guaraní is spoken in the southeast.

Bolivia has 12 million inhabitants. Only 5 languages of Bolivia are spoken by more than 30,000 people: Spanish monolingual (5 million speakers), Kichwa (2.4 million speakers), Aymara (1.5 million), Low German (Plattdeutsch) (100,000 speakers) and Guaraní (33,000 speakers). Of these all are official except Plattdeutsch. There are 8 official languages spoken by between 1,000 and 8,000 people each. So of the 37 languages declared official by the constitution of 2009, 23 are spoken by less than 1,000 people and 2 are extinct (puquina and machajuyai-kallawaya).

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