Sir Harbottle Grimston, 2nd Baronet (27 January 1603 – 2 January 1685) was an English lawyer and politician who sat in the House of Commons at various times between 1640 and 1685 and was Speaker in 1660. During the English Civil War he remained a Parliamentarian but was sympathetic to the Royalists.

Grimston was among the secluded members who re-entered the restored Rump Parliament in February 1660, was then a member of the council of state. He was chosen Speaker of the House of Commons in the Convention Parliament of 1660. As Speaker he visited Charles II at Breda, and addressed him in very flattering terms on his return to London; but he refused to accede to the King's demand that he should dismiss Burnet from his position as chaplain to the Master of the Rolls, and in parliament he strongly denounced any relaxation of the laws against papists.

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