Lake Sakakawea is a reservoir in the north central United States, located in the Missouri River basin in central North Dakota. It is the largest man-made lake in the state and the third largest in the nation, after Lake Mead and Lake Powell.

The creation of the lake displaced members of the Fort Berthold Indian Reservation from their villages of Van Hook and (Old) Sanish, which were inundated by creation of the lake. They relocated and founded the villages of New Town, White Shield, and Mandaree. Elbowoods, a third reservation town where the agency headquarters, boarding school, hospital, and jail were located, was also lost to the lake. These three towns are commemorated in the names of the three campground sections at Lake Sakakawea State Park, a state park located adjacent to Garrison Dam.

Lake Sakakawea has a maximum water storage of 23,800,000 acre feet, a maximum water depth: 180 feet (55 m). It has a surface area of 307,000 acres (480 sq mi), a length of 178 miles (286 km), and a shoreline of 1,320 mi (2,120 km).

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