'Slaughterhouse-Five', or 'The Children's Crusade: A Duty-Dance with Death' (1969) is a science fiction-infused anti-war novel by Kurt Vonnegut about the World War II experiences and journeys through time of Billy Pilgrim, from his time as an American soldier and chaplain's assistant, to postwar and early years. It is generally recognized as Vonnegut's most influential and popular work. A central event is Pilgrim's surviving the Allies' firebombing of Dresden as a prisoner-of-war. This was an event in Vonnegut's own life, and the novel is considered semi-autobiographical.

A film adaptation of the book, also called 'Slaughterhouse-Five', was released in 1972. Although critically praised, the film was a box office flop. It won the Prix du Jury at the 1972 Cannes Film Festival, as well as a Hugo Award and Saturn Award. Vonnegut commended the film greatly. In 2013, Guillermo del Toro announced his intention to remake the 1972 film and work with a script by Charlie Kaufman, originally hoping to release it in early 2011. Due to his involvement with The Hobbit, the project was pushed back and remains uncertain.

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