"The Last Supper" is one of the most famous painting by Leonardo da Vinci, and it is in the refectory of the Convent of Santa Maria delle Grazie, Milan.

Leonardo da Vinci started this work around 1495-1496. It was commissioned as part of a plan of renovations to the church and its convent buildings by Leonardo's patron Ludovico Sforza, Duke of Milan. Due to the painting methods used, and a variety of environmental factors, as well as some intentional damage, very little of the original painting remains today. During World War II, on August 15, 1943, the refectory was struck by Allied bombing; protective sandbagging prevented the painting from being struck by bomb splinters, but it may have been damaged further by the vibration. From 1951 to 1954, a cleaning and stabilizing restoration was undertaken. Other restoration attempts have been made over the years, the last being completed in 1999.

The painting represents the scene of the meal Jesus ate with twelve disciples on the night he was betrayed. This comes from of Gospel of John chapter 13. Leonardo has depicted the confusion and concern that occurred among the twelve when Jesus announced that one of them would betray him. Notice that the painting includes all twelve men plus Jesus, indicating that Judas had not left the scene yet.

More Info: en.wikipedia.org