The Panamanian golden frog (Atelopus zeteki) is a species of toad endemic to Panama. Panamanian golden frogs inhabit the streams along the mountainous slopes of the Cordilleran cloud forests of west-central Panama. While the IUCN lists it as critically endangered, it may in fact have been extinct in the wild since 2007. Individuals have been collected for breeding in captivity in a bid to preserve the species. The alternative common name, Zetek's golden frog, and the epithet zeteki both commemorate the entomologist James Zetek.

Despite its common name, the Panamanian golden frog is a true toad, a member of the family Bufonidae. It was first described as a subspecies of Atelopus varius, but is now classified as a separate species.

The Panamanian golden frog is a national symbol and is considered to be one of the most beautiful frogs in Panama.The skin colour ranges from light yellow-green to bright gold, with some individuals exhibiting black spots on their backs and legs. Females are generally larger than males; females typically range from 45 to 63 mm (1.8 to 2.5 in) in length and 4 to 15 g (0.14 to 0.53 oz) in weight, with males between 35 and 48 millimetres (1.4 and 1.9 in) in length and 3 and 12 grams (0.11 and 0.42 oz) in weight.

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