Whoville, sometimes written as Who-ville, is a fictional town created by author Theodor Seuss Geisel, under the name Dr. Seuss. Whoville appeared in the 1954 book Horton Hears a Who! and the 1957 book How the Grinch Stole Christmas!; with significant differences between the two renditions. Its denizens go by the collective name Whos, as in a plural form of the pronoun who.

Many of the different characters, known as Whos, live within the speck that contains Whoville. The Whos are whimsical, animal-like creatures who live in shaped houses, known for their warm hearts and welcoming spirits. They are small, furry humanoids with canine snouts and 12 toes. As they celebrate Christmas and readily recognize its true meaning in the absence of material gifts, it is implied to be a majority Christian community; Seuss had gone through several attempts at a more explicitly Christian ending to How the Grinch Stole Christmas! but, dissatisfied in the idea of a heavy-handed approach, decided to leave the religious aspects implied. In the live-action film, however, the Whos resemble ordinary people with large ears, buck-teeth and strange hairstyles, and while the Who children have ordinary human noses, the adult Whos' noses are snout shaped. Also, they are shown to be very greedy and materialistic as compared to the book version. Just north of Whoville, atop a high mountain, Mount Crumpit, a bitter, cave-dwelling creature named the Grinch lives with his dog, Max.

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