The Symphony No. 38 was composed by Wolfgang Amadeus Mozart in late 1786. It was premiered in Prague on January 19, 1787, during Mozart's first visit to the city. Because it was first performed in Prague, it is popularly known as the Prague Symphony. Mozart's autograph thematic catalogue records December 6, 1786, as the date of completion for this composition.

Although Mozart's popularity among the Viennese waxed and waned, he was consistently popular among the Bohemians and had a devoted following in Prague. In spite of the fact that the Symphony No. 38 was first performed in Prague, it is not certain that it was actually written for Prague.

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