Apollo 17 (December 7–19, 1972) was the final Moon landing mission of NASA's Apollo program, and remains the most recent time humans have travelled beyond low Earth orbit. Its crew consisted of Commander Eugene Cernan, Lunar Module Pilot Harrison Schmitt, and Command Module Pilot Ronald Evans, and it carried a biological experiment containing five mice.

Officially, the mice—four male and one female—were assigned the identification numbers A3326, A3400, A3305, A3356 and A3352. Unofficially, according to Cernan, the Apollo 17 crew dubbed them Fe, Fi, Fo, Fum, and Phooey.

Cernan and Schmitt landed in the Taurus–Littrow valley and completed three moonwalks, taking lunar samples and deploying scientific instruments. The landing site had been chosen to further the mission's main goals: to sample lunar highland material older than Mare Imbrium, and to investigate the possibility of relatively recent volcanic activity. Evans remained in lunar orbit in the command and service module (CSM), taking scientific measurements and photographs.

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