Which organ has the most fat?

The human brain is the fattest organ in your body and consists of about 60 percent fat. Twenty five percent cholesterol and other lipids.

How can one of our most important organs contain so much fat? When you think about what it takes to make a brain work, in terms of power, the answer becomes clearer. Your brain generates enough watts to power a light bulb (roughly 20 watts). We all use nearly 100% of our brains (not 10%) and fats are vital to a healthy diet. Fats perform many functions in our body including absorbing fat-soluble vitamins, hormone synthesis, inflammation, temperature regulation, energy production, and much more. The brain is capable on obtaining about 70% of its energy solely from fat, namely ketones.

In fact, better memory functioning is associated with higher total and low-density lipoprotein cholesterol levels in very elderly subjects (study NIH). The researchers showed that in the elderly, the best memory function was observed in those with the highest levels of cholesterol. Low cholesterol is associated with an increased risk for depression and even death.