In Jacksonville, Florida, during the summer of 1964, Ronnie Van Zant, Bob Burns, and Gary Rossington became acquainted while playing on rival baseball teams. The trio decided to jam together one afternoon after Burns was injured by a ball hit by Van Zant. They set up their equipment in the carport of Burns' parents' house and played The Rolling Stones' then-current hit "Time Is on My Side". They then convinced guitarist Allen Collins to join the band. Bassist Larry Junstrom soon rounded out the lineup and the band settled on the name My Backyard, later changed to The Noble Five before becoming The One Percent by 1968.

Still known as The One Percent in 1969, Van Zant sought a new name. At Burns' suggestion, the group settled on Leonard Skinnerd, a mocking tribute to P.E. teacher Leonard Skinner at Robert E. Lee High School. Skinner was notorious for strictly enforcing the school's policy against boys having long hair. Rossington dropped out of school, tired of being hassled about his hair. The more distinctive spelling "Lynyrd Skynyrd" was being used at least as early as 1970. Despite their high school acrimony, the band developed a friendlier relationship with Skinner in later years and invited him to introduce them at a concert in the Jacksonville Memorial Coliseum. Skinner also allowed the band to use a photo of his Leonard Skinner Realty sign for the inside of their third album.

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