Knowsley Road in Eccleston, St Helens, Merseyside, was the home ground of St. Helens from 1890 until its closure in 2010. St Helens Town FC played their home fixtures at Knowsley Road from 2002 until 2010. For a period, the venue also hosted Liverpool F.C. Reserves. The stadium was demolished during spring 2011 and a new construction then known as Cunningham Grange, named after club legend Keiron Cunningham, was built on the site.

St. Helens moved to Knowsley Road in 1890, defeating Manchester Rangers in their first match. The stadium pre-dated the birth of the Northern Rugby Football Union (which would later become rugby league) by five years. Having been formed in 1873, St. Helens were a rugby union club when they moved into Knowsley Road. The stadium changed in appearance very little in its 120 years.

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