William and Mary College is located on a 1,200-acre (490 ha) campus in Williamsburg, Virginia. In 2011, Travel+Leisure named William & Mary one of the most beautiful college campuses in the United States.

The Sir Christopher Wren Building is the oldest college building in the United States and a National Historic Landmark. The building, colloquially referred to as the "Wren Building", was named upon its renovation in 1931 to honor the English architect Sir Christopher Wren. The basis for the 1930s name is a 1724 history in which Hugh Jones stated the 1699 design was "first modelled by Sir Christopher Wren" and then was adapted "by the Gentlemen there" in Virginia; little is known about how it looked, since it burned within a few years of its completion. Today's Wren Building is based on the design of its 1716 replacement. The College's Alumni Association recently published an article suggesting Wren's connection to the 1931 building is a viable subject of investigation.

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