Mary Morstan is the wife of Dr. Watson. She is first introduced in The Sign of the Four, where she and Watson tentatively become attracted to each other, but only when the case is resolved is he able to propose to her. She is described as blonde with pale skin. At the time she hires Holmes she had been making a living as a governess. Although at the end of the story the main treasure is lost, she has received six pearls from a chaplet of the Agra Treasure.

Her father, Captain Arthur Morstan, was a senior captain of an Indian regiment and later stationed near the Andaman Islands. He disappeared in 1878 under mysterious circumstances that would later be proven to be related to the mystery, The Sign of the Four. Her mother died soon after her birth and she had no other relatives in England, although she was educated there (in accordance with the received wisdom of the time about children in the colony of India) until the age of seventeen. Shortly afterwards her father disappeared and she found work as a governess. Watson and Mary marry in 1889.

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